KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IREB2
All Species:
22.73
Human Site:
T728
Identified Species:
35.71
UniProt:
P48200
Number Species:
14
Phosphosite Substitution
Charge Score:
0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48200
NP_004127.1
963
105047
T728
P
S
F
F
D
K
L
T
K
E
P
I
A
L
Q
Chimpanzee
Pan troglodytes
XP_523125
963
104993
T728
P
S
F
F
D
K
L
T
K
E
P
I
A
L
Q
Rhesus Macaque
Macaca mulatta
XP_001107837
964
105069
T729
P
S
F
F
D
K
L
T
K
E
P
V
A
L
Q
Dog
Lupus familis
XP_532364
964
105327
T729
P
S
F
F
D
K
L
T
K
E
P
V
A
L
R
Cat
Felis silvestris
Mouse
Mus musculus
Q811J3
963
104918
T728
P
S
F
F
D
K
L
T
K
E
P
A
A
S
Q
Rat
Rattus norvegicus
Q62751
963
104783
T728
P
S
F
F
D
K
L
T
K
E
P
A
A
S
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513243
1011
110449
A776
P
S
F
F
D
K
L
A
K
E
P
A
V
L
E
Chicken
Gallus gallus
Q5ZLQ4
965
105344
A730
P
S
F
F
D
K
L
A
K
E
P
V
S
L
Q
Frog
Xenopus laevis
Q6NTP2
955
104418
E720
P
P
F
F
H
K
L
E
K
I
P
P
P
I
Q
Zebra Danio
Brachydanio rerio
XP_001341791
896
98752
S665
K
M
S
K
E
V
C
S
P
Q
S
I
D
G
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524303
899
98560
D665
F
F
E
G
M
T
R
D
L
P
K
L
Q
S
I
Honey Bee
Apis mellifera
XP_392993
890
98796
R668
I
K
S
I
T
K
A
R
V
L
L
N
L
G
D
Nematode Worm
Caenorhab. elegans
Q23500
887
96642
L666
D
I
V
N
A
H
V
L
L
N
L
G
D
S
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q42560
898
98134
D677
Y
C
L
L
N
F
G
D
S
I
T
T
D
H
I
Baker's Yeast
Sacchar. cerevisiae
P19414
778
85350
D560
V
K
V
S
P
T
S
D
R
L
Q
L
L
K
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.1
92.5
N.A.
93.6
93.8
N.A.
84.4
82.1
68.5
62.9
N.A.
54.5
55.5
52.3
N.A.
Protein Similarity:
100
99.6
99.6
96.8
N.A.
96.6
97.1
N.A.
89.9
91.1
81
77
N.A.
72.4
71.8
67.5
N.A.
P-Site Identity:
100
100
93.3
86.6
N.A.
86.6
86.6
N.A.
73.3
80
53.3
6.6
N.A.
0
6.6
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
86.6
86.6
N.A.
80
93.3
60
26.6
N.A.
6.6
6.6
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
49.1
26
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
65.5
42.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
0
7
14
0
0
0
20
40
0
7
% A
% Cys:
0
7
0
0
0
0
7
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
0
54
0
0
20
0
0
0
0
20
0
7
% D
% Glu:
0
0
7
0
7
0
0
7
0
54
0
0
0
0
7
% E
% Phe:
7
7
60
60
0
7
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
7
0
0
7
0
0
0
0
7
0
14
0
% G
% His:
0
0
0
0
7
7
0
0
0
0
0
0
0
7
0
% H
% Ile:
7
7
0
7
0
0
0
0
0
14
0
20
0
7
14
% I
% Lys:
7
14
0
7
0
67
0
0
60
0
7
0
0
7
0
% K
% Leu:
0
0
7
7
0
0
60
7
14
14
14
14
14
40
0
% L
% Met:
0
7
0
0
7
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
7
7
0
0
0
0
7
0
7
0
0
0
% N
% Pro:
60
7
0
0
7
0
0
0
7
7
60
7
7
0
7
% P
% Gln:
0
0
0
0
0
0
0
0
0
7
7
0
7
0
47
% Q
% Arg:
0
0
0
0
0
0
7
7
7
0
0
0
0
0
7
% R
% Ser:
0
54
14
7
0
0
7
7
7
0
7
0
7
27
0
% S
% Thr:
0
0
0
0
7
14
0
40
0
0
7
7
0
0
0
% T
% Val:
7
0
14
0
0
7
7
0
7
0
0
20
7
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _